Sanjay Popat, BSc, MBBS, FRCP, PhD, The Royal Marsden NHS Foundation Trust, London, UK, discusses the impact of the approval of atezolizumab in UK patients with PD-L1-positive non-small cell lung cancer (NSCLC). Approval of the anti-PD-L1 antibody in England was made possible via Project Orbis, and atezolizumab demonstrated superior disease-free survival in the IMpower010 trial (NCT02486718). Prof. Popat additionally highlights the need for PD-L1 testing to identify patients who will benefit from this treatment. This interview took place at the 20th Annual British Thoracic Oncology Group (BTOG) Conference 2022.