Arjun Balar, MD, NYU Langone Health Perlmutter Cancer Center, New York City, NY, discusses extended follow-up results of cohort A from the Phase II KEYNOTE-057 study (NCT02625961) investigating pembrolizumab for the treatment of patients with high-risk non-muscle-invasive bladder cancer (NMIBC). 96 patients who were treated with pembrolizumab were included in the efficacy analysis. At a median follow-up of 36.4 months, the complete response rate was 40.6% and the median duration or response was 16.2 months. This interview took place during the 2021 Genitourinary Cancers Symposium.