ESMO Breast 2024 | PREcoopERA: giredestrant versus anastrozole in ER+/HER2- early breast cancer

Elisabetta Munzone, MD, Istituto Europeo di Oncologia, Milan, Italy, provides an overview of the Phase III, window-of-opportunity (WOO) PREcoopERA trial (NCT05896566), which aims to assess giredestrant, an oral selective ER degraders (SERD), with or without LHRH agonist versus anastrozole in premenopausal women with ER+/HER2- early breast cancer. The primary endpoint is change in Ki-67 labeling index between pre-treatment diagnostic tumor biopsy and post-treatment rebiopsy. This interview took place at the 2024 European Society for Medical Oncology (ESMO) Breast Cancer Annual Congress in Berlin, Germany.

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