Philipp Karschnia, MD, Ludwig-Maximilians-University of Munich, Munich, Germany, discusses the international Response Assessment in Neuro-Oncology (RANO) resect group and the development of a classification system for the extent of surgery in patients with glioblastoma. This classification is highly prognostic and may serve fo the stratification and design on clinical trials. This interview took place at the American Society of Clinical Oncology (ASCO) 2022 Annual Meeting in Chicago, IL.