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ASCO 2024 | Opportunities in MRD detection and intervention in multiple solid tumors
Scott Kopetz, MD, PhD, The University of Texas MD Anderson Cancer Center, Houston, TX, highlights methodologies to improve patient outcomes through minimal residual disease (MRD) detection. Examples include the use of precise assays to detect smaller amounts of disease in patients with melanoma, as well as in those with pancreatic and colorectal cancers. Such techniques can also help detect MRD after surgical resection and allow more patients to benefit from more directed, novel therapies including immunotherapies. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.
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Disclosures
Stock and Other Ownership Interests – Frontier Medicines; Iylon; Lutris; Navire; Xilis
Consulting or Advisory Role – Abbvie; Accademia Nazionale Di Medicina (ACCMED); Amal Therapeutics; Amgen; AstraZeneca/MedImmune; AVEO; Bayer Health; Bicara Therapeutics; Black Diamond Therapeutics; Boehringer Ingelheim; Bristol-Myers Squibb/Medarex; Cardiff Oncology; Carina Biotech; CureTeq; EMD Serono; Endeavor BioMedicines; Flame Biosciences; Foundation Medicine; Frontier Medicines; Genentech; Genomic Health; Gilead Sciences; GlaxoSmithKline; HalioDx; Harbinger Oncology, Inc; Holy Stone Healthcare; Inivata; Ipsen; Iylon; Jacobio; Jazz Pharmaceuticals; Johnson & Johnson/Janssen; Lilly; Lutris; Merck; Mirati Therapeutics; NeoGenomics Laboratories; Novartis; Numab; Ono Pharmaceutical; Pfizer; Redx Pharma; Repare Therapeutics; Replimune; Roche; Sanofi; Servier; Tachyon Therapeutics; Taiho Pharmaceutical; Takeda; Tempus; Xilis; Zentalis
Research Funding – Amgen; Array BioPharma; Biocartis; Daiichi Sankyo; EMD Serono; Genentech/Roche; Guardant Health; Lilly; MedImmune; Novartis; Sanofi
