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WCLC 2024 | Phase III trial of divarasib versus adagrasib or sotorasib in KRAS G12C-m NSCLC
Shirish Gadgeel, MD, Henry Ford Cancer Institute/Henry Ford Health, Detroit, MI, discusses a Phase III trial (EudraCT: 2024-510908-37-00) of divarasib, an oral KRAS G12C inhibitor, compared to adagrasib or sotorasib in patients with previously treated KRAS G12C-mutated advanced/metastatic non-small cell lung cancer (NSCLC). Divarasib has demonstrated promising antitumor activity with an acceptable safety profile in previous studies. The primary endpoint in this trial will be progression-free survival. This interview took place at the 2024 World Conference on Lung Cancer (WCLC) in San Diego, CA.
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