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SABCS 2024 | Prognostic impact of micrometastatic residual disease in node-negative breast cancer

Johannes Holtschmidt, MD, German Breast Group, Neu-Isenburg, Germany, examines the risks associated with understaging high-risk node-negative breast cancer patients receiving neoadjuvant treatment. Patients with micrometastatic residual disease, particularly those initially assessed as lower risk, tend to have a poor prognosis. These outcomes highlight the challenges of identifying node-positive cases and the need for systemic therapy options in the post-neoadjuvant setting, rather than relying solely on surgical or local regional approaches, to address recurrence risks and improve long-term outcomes. This interview took place at the 2024 San Antonio Breast Cancer Symposium (SABCS) congress in San Antonio, TX.

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