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ESSO 44 | The evolving surgical approach to retroperitoneal sarcoma

Marco Fiore, MD, FACS, IRCCS National Cancer Institute, Milan, Italy, discusses the evolving surgical approach to retroperitoneal sarcoma, a rare disease with only 400-500 cases per year in Italy, and highlights the importance of a comprehensive retroperitoneal resection for optimal local control, which may involve resecting surrounding organs. Dr Fiore emphasizes the need for a structured approach to treating this disease, similar to other fields of surgical oncology, and notes that this approach is particularly important for liposarcoma, the most frequent histology encountered. This interview took place at the 44th Congress of the European Society of Surgical Oncology (ESSO 44) in Gothenburg, Sweden.

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Transcript

Yeah, sure. The surgical approach to retroperitoneal sarcoma is a very hot topic. It has been changing, actually, over the last years. So it’s very important to have some education and training also. So this kind of approach that is very specific to a rare disease like retroperitoneal sarcoma that accounts for example in Italy for no more than 400 to 500 cases per year, so it’s a rare tumor...

Yeah, sure. The surgical approach to retroperitoneal sarcoma is a very hot topic. It has been changing, actually, over the last years. So it’s very important to have some education and training also. So this kind of approach that is very specific to a rare disease like retroperitoneal sarcoma that accounts for example in Italy for no more than 400 to 500 cases per year, so it’s a rare tumor. Besides that, the approach is specific because from the technical point of view, these are not organ tumors, they just grow wherever within the abdomen, within the spaces in the retroperitoneal space, which is difficult and sometimes challenging to be approached. More importantly, we found out over the last years that the best local control of these diseases is reached when you offer a very extensive procedure that we call a comprehensive retroperitoneal resection. That means that you can resect also surrounding organs to the tumor, regardless of whether they are directly invaded or not by the sarcoma. This is applied especially for liposarcoma, the more frequent histology encountered. It’s a little bit different in case of leiomyosarcoma, which is the second one. But besides that, we think that offering a very structured approach, as we have in all the other fields of surgical oncology – I mean, you have a very structured approach to pancreatic duodenectomy, to mesorectal excision, and so on – so why should you not have this for the optimal treatment of retroperitoneal sarcoma? So we really think that this is important and it’s all still not completely outside of a referral center.

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