I think no. No, today with the data that we have. Because here it was just the trial is done and you just do a correlation. But you are not sure that the patient that clears ctDNA doesn’t need the adjuvant treatment that we gave to this patient today. So I will not dare to do that today. If the patient clears CT DNA, I will not dare to de-intensify with this kind of data...
I think no. No, today with the data that we have. Because here it was just the trial is done and you just do a correlation. But you are not sure that the patient that clears ctDNA doesn’t need the adjuvant treatment that we gave to this patient today. So I will not dare to do that today. If the patient clears CT DNA, I will not dare to de-intensify with this kind of data. Because be aware that if you look carefully at the curve, around 40% of the patients that clear CT DNA still relapse. So I will be extremely careful with the data that we have today to do a de-escalation. The other way around, if you have CT DNA positive, I think your prognosis is worse. It’s probably a reason to intensify the treatment of this patient.
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