Matteo Lambertini, MD, PhD, IRCCS AOU San Martino (Ospedale Policlinico San Martino), Genova, Italy, discusses the recently published ESMO Clinical Practice Guidelines in fertility preservation and post-treatment pregnancies in post-pubertal cancer patients, these include sperm cryopreservation and oocyte/embryo cryopreservation, ovarian tissue cryopreservation and that post-treatment pregnancies in breast cancer survivors should not be discouraged. This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).