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ESMO 2022 | Subgroup analysis of PEARLS/KEYNOTE-091: PD-L1 expression and outcomes of pembrolizumab

Solange Peters, MD, PhD, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland, presents the results of a subgroup analysis of PEARLS/KEYNOTE-091 (NCT02504372) which demonstrated an improved disease-free survival in patients treated with pembrolizumab compared with placebo. Disease-free survival in the PD-L1 tumor proportion score (TPS) less than 50% population was not significant, which was likely due to placebo overperformance and a smaller population size. This interview took place at the European Society for Medical Oncology (ESMO) 2022 Congress in Paris, France.

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