Solange Peters, MD, PhD, University Hospital Vaudois, Lausanne, Switzerland, discusses the final analysis of the part 1 CheckMate-227 trial (NCT02477826), which investigated the use of nivolumab, or nivolumab plus ipilimumab, or nivolumab plus platinum-doublet chemotherapy, compared to platinum doublet chemotherapy in patients with stage IV non-small cell lung cancer (NSCLC). This interview took place at the European Society for Medical Oncology (ESMO) 2019 congress in Barcelona, Spain.