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ELCC 2025 | The impact of durvalumab on the SCLC treatment landscape

Suresh Senan, MRCP, FRCR, PhD, Amsterdam University Medical Centers, Amsterdam, Netherlands, comments on the current status of durvalumab in the treatment of small cell lung cancer (SCLC). Durvalumab has obtained global regulatory approval following the ADRIATIC trial (NCT03703297), but the NRG-LU005 (NCT03811002) showed that concurrent immunotherapy and chemoradiotherapy was not as efficacious. Further trials are need to determine the optimal timing and approach of immunotherapy, including sequential and concurrent regimens, to establish the best standard of care for this patient population. This interview took place at the European Lung Cancer Congress (ELCC) 2025 in Paris, France.

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