Simon Crabb, PhD, MBBS, from the University of Southampton in Southampton, UK, discusses findings from the MANCAN2 trial regarding the use of cognitive-behavioral therapy (CBT) for managing hot flushes in prostate cancer patients. While the trial demonstrated short-term benefits of CBT in reducing the severity of hot flushes, Prof. Crabb emphasizes the need for further research to optimize the dose and long-term efficacy of CBT. This includes exploring the potential for booster sessions and strategies to help patients maintain the benefits of CBT over time. Additionally, the trial revealed that men receiving CBT were more likely to adhere to hormonal therapy, suggesting broader implications for treatment adherence beyond managing hot flushes. These findings underscore the importance of continued investigation into the role of CBT in improving quality of life and treatment outcomes for prostate cancer patients. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.
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