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ASCO 2024 | Short-term benefits of self-help CBT for managing hot flushes in prostate cancer patients on ADT

Simon Crabb, PhD, MBBS, University of Southampton, Southampton, UK, discusses the findings of the MANCAN2 trial on the impact of self-help cognitive-behavioral therapy (CBT) for managing hot flushes in prostate cancer patients undergoing androgen deprivation therapy (ADT). With 80% of these patients experiencing significant hot flushes along with depression, anxiety, and compliance issues, non-pharmacological interventions like CBT present an ideal solution. The trial trained prostate cancer nurses to deliver CBT, showing effective reproduction of group sessions without the need for clinical psychologists. This approach demonstrated short-term improvements in symptoms, though further research is needed to sustain benefits long-term. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

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