Well, that’s a really good question because mainly it has an easy and a really difficult response. First is going to be patient selection and tailor-made treatment for each patient. But in our study, we found that younger patients, nodal involvement, lack of neoadjuvant treatment, lack of radiation therapy, and lobular carcinoma, and also, of course, multicentric disease have a higher risk of positive margins...
Well, that’s a really good question because mainly it has an easy and a really difficult response. First is going to be patient selection and tailor-made treatment for each patient. But in our study, we found that younger patients, nodal involvement, lack of neoadjuvant treatment, lack of radiation therapy, and lobular carcinoma, and also, of course, multicentric disease have a higher risk of positive margins. But on the contrary, older age, over 70 years old, or luminal B tumor, were less likely to have a re-excision of margins. But having said that, you need to go case by case and just tailor-made your treatment to each patient after a breast-conservative surgery you need to achieve clear margins because if you don’t you have a higher risk of local relapse or lower survival but if you want to perform this conservative surgery you need to have optimal breast appearance. You need to have a good cosmetic result. So you need to do it again case by case. You need to bear in mind the amount of tissue you want to take out and also bear in mind that you always want to have negative margins. And you also need to talk to your patients just to let her know that you have a rate of resection of around 6% and that way she needs to understand that she has a 6% chance of going back to the OR and that may have an impact on her patient satisfaction scores.
This transcript is AI-generated. While we strive for accuracy, please verify this copy with the video.
