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GU Cancers 2026 | Global expansion of PC-PEP improves equity in prostate cancer care

Gabriela Ilie, PhD, Dalhousie University, Halifax, Canada, provides an overview of PC-PEP, a comprehensive home-based program developed in 2019 that addresses key factors in patient care. Positive results have previously been reported in terms decreasing mental health issues and improving urinary and sexual function in patients with prostate cancer. The program is being tested on four continents and has shown benefits for various populations, including men in rural areas, LGBTQ+ men, indigenous men, and black men, with a particular focus on health equity and tailoring the program to meet the unique needs of each group. This interview took place at the 2026 ASCO GU Cancers Symposium in San Francisco, CA.

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Transcript

We’re really delighted with this program, this intervention we developed back in 2019. It’s a daily, comprehensive, home-based program that really addresses this X factor. And we tested the intervention. So daily, for six months, it’s the longest intervention in the world. And so we tested it through a randomized clinical trial against usual care. We found that there are positive results in terms of decreasing mental health issues, improving urinary function, sexual function, especially among surgery patients...

We’re really delighted with this program, this intervention we developed back in 2019. It’s a daily, comprehensive, home-based program that really addresses this X factor. And we tested the intervention. So daily, for six months, it’s the longest intervention in the world. And so we tested it through a randomized clinical trial against usual care. We found that there are positive results in terms of decreasing mental health issues, improving urinary function, sexual function, especially among surgery patients. And we went into expanding the trial to a pan-Canadian international trial. We are now on four continents testing this to see what works for whom under what conditions. And we also received funding from November to look at health equity. And so we’re looking at, you know, do we need to tweak the program for men living in rural areas compared to urban LGBTQ+ community, indigenous men. So we’re working with the Congress of Aboriginal People, for example, and we’re working with LGBTQ+ organizations, and what we’re finding is that actually the program is very well suited, it’s just as well suited for rural as it is for urban places and men in those communities, but also especially useful for LGBTQ+ men who have much higher needs, much higher levels of anxiety at the start when they get diagnosed, and they benefit more from being part of the program. Lack of attrition is particularly high in this population. Black men particularly benefit from the program as well, just as much as the rest of the population, but especially with regards to urinary function. And we’re finding that younger men, a population that is almost overlooked, men that are younger than 60, that have different needs. You know, they’re still young, they want to have kids and so on. And so this program is particularly beneficial for them. But of course, there are tweaks to the program that you need to make to really meet the needs of the population. That is why it’s so important to bring the voice of the patient into those interventions as you move them along in implementing them in other parts of the world and also in various geographic locations.

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