BNOS 2022 | Delivering drugs to the brain with nanoparticles

Christopher McConville, PhD, University of Birmingham, Birmingham, UK, discusses the potential role of nanoparticles as a method of drug delivery in treating brain tumors. Early constrains include the use of solvents in producing nanoparticles which limits the use in clinical settings. The advent of microfluidics has resulted in a scalable, solvent-free method of manufacturing nanoparticles that can cross the blood-brain barrier. However, there are a few good manufacturing practice (GMP)-compliant facilities to mass-manufacture nanoparticles, which will be needed to assess their efficacy in clinical trials. This interview took place at the British Neuro-Oncology Society (BNOS) Annual Meeting 2022.