Philip Poortmans, MD, PhD, AZ Sint-Augustinus – Oncologisch Centrum GZA – Iridium Kankernetwerk, Antwerpen, Belgium, discusses treatment strategies for oligometastatic breast cancer, as discussed during the European Society for Medical Oncology (ESMO) Breast Cancer 2022 congress. Dr Poortmans highlights the role of surgery, ablative radiation therapy and systemic treatment approaches. This interview took place at the European Society for Medical Oncology (ESMO) Breast Cancer 2022 congress in Berlin, Germany.