Jarushka Naidoo, MBBCh, MHS, Beaumont Hospital, Dublin, Ireland, shares an update on translational research from BTOG 2021, in particular talking on antibody drug conjugates and the targeting of KRAS in lung cancer treatment. Dr Naidoo outlines the use of sotorasib and adagrasib, both of which target KRAS G12C-mutant lung cancer. Dr Naidoo also gives an overview of the use of cellular therapies in the treatment of lung cancer, describing tumor infiltrating lymphocyte (TIL) therapy. This interview took place during the 19th British Thoracic Oncology Group (BTOG) Annual Conference 2021.