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ESMO 2026 | Highlights in brain metastasis research at ESMO 2026

Ariane Steindl, PhD, Medical University of Vienna, Vienna, Austria, discusses the highlights in brain metastasis research presented at ESMO 2026, noting the increased inclusion of these patients in lung and breast cancer trials, but emphasizing the need for more data on patients with active brain metastases. Dr Steindl highlights the promising results of the TUXEDO-3 (NCT05865990) trial, which demonstrated the efficacy of antibody-drug conjugates (ADCs) in patients with active brain metastasis from lung cancer, breast cancer, and leptomeningeal disease. This interview took place at the European Society for Medical Oncology (ESMO) 2026 Congress in Madrid, Spain.

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