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ESMO 2026 | Current evidence does not recommend thoracic radiotherapy for esSCLC

Bjorn Henning Gronberg, MD, PhD, Norwegian University of Science and Technology, Trondheim, Norway, explores the current evidence base for thoracic radiotherapy in extensive-stage small cell lung cancer (esSCLC) in the immunotherapy era, highlighting that recent studies have shown no indication of benefit and increased fatal events with the addition of thoracic radiotherapy to chemoimmunotherapy. Evidence suggests therefore that thoracic radiotherapy should not be offered to patients with patients esSCLC receiving chemoimmunotherapy, except for those with symptomatic tumor progression who may benefit from palliative radiotherapy. This interview took place at the European Society for Medical Oncology (ESMO) 2026 Congress in Madrid, Spain.

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