Sandra Swain, MD, FACP, Georgetown University Medical Center, Washington, DC, discusses CLEOPATRA (NCT00567190), a phase III, randomized, double-blind, placebo-controlled study of first-line pertuzumab, trastuzumab, and docetaxel in patients with HER2+ metastatic breast cancer (mBC). This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).