Declan Murphy, FRACS, FRCS, Peter MacCallum Cancer Centre, Melbourne, Australia, discusses the limitations of next-generation imaging tools like whole body magnetic resonance imaging (MRI) and prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) in prostate cancer. PSMA PET/CT has been shown to be the best modality for staging prostate cancer, surpassing whole body MRI. Limitations include variability in tracer efficacy, with PSMA-1007 showing high uptake in benign bone lesions. This interview took place at the 2024 Advanced Prostate Cancer Consensus Conference (APCCC) in Lugano, Switzerland.
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