Gizem Öner, MD, Istanbul University, Istanbul, Türkiye, discusses research on how clinicians interpret preclinical studies in clinical practice, focusing on the tumor microenvironment (TME) and its impact on personalized cancer treatment. The research specifically investigates the role of macrophages (Mφ) in the TME, particularly their contribution to chemotherapy resistance. The study uses immunochemical analysis (CD68 and CD163 markers) to assess macrophage infiltration and its correlation with chemotherapy response. While promising, further research is needed to translate these findings into clinical practice.This interview took place at the ESSO 43 congress in Antwerp, Belgium.
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