Susan Halabi, PhD, FSCT, FASA, FASCO, Duke Cancer Institute, Durham, NC, describes how established risk factors can be integrated with genomic alterations to classify patients with metastatic castrate-resistant prostate cancer (mCRPC) into risk groups. Previous models have successfully classified patients based on overall survival. Integration of genomic alterations to established risk factors improves risk stratification and has now been used to classify patients for radiographic progression-free survival (rPFS). This interview took place during the 2026 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.
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