ESMO 2023 | LUPER: lurbinectedin in combination with pembrolizumab in relapsed SCLC

Antonio Calles Blanco, MD, Gregorio Maranon General University Hospital, Madrid, Spain, discusses results from the LUPER study (NCT04358237), which investigated the efficacy and safety of lurbinectedin in combination with pembrolizumab as a second-line treatment for relapsed small cell lung cancer (SCLC). The preliminary overall response rate was 46.4%, with a median duration of response of 11.4 months. The combination demonstrated effectiveness with manageable safety, suggesting its potential as a second-line therapy for SCLC, warranting further investigation. This interview took place at the European Society for Medical Oncology (ESMO) 2023 Congress in Madrid, Spain.

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