Alexander Spira, MD, PhD, FACP, Virginia Cancer Specialists, Fairfax, VA, emphasizes the importance of MET Exon 14 (METex14) mutation testing in patients with non-small cell lung cancer (NSCLC), as well as biomarker testing in general to allow patients to be offered targeted therapies. He highlights that patients with NSCLC that test positive for METex14 skipping mutations should be offered capmatinib and tepotinib in all lines of therapy. This interview took place at the World Conference on Lung Cancer (WCLC) 2021.