Leonora Slatnick, MD, University of Utah, Salt Lake City, UT, provides an overview of managing central nervous system (CNS) metastases in pediatric patients with Ewing sarcoma (ES). The lack of standardized management and the poor outcomes for these patients are highlighted. Although outcomes may differ from other metastatic or relapsed diseases, the small cohort size makes it unclear. One case involved a patient with incomplete resection who underwent high-dose chemotherapy with stem cell rescue and achieved long-term survival, which is unusual. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.
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