Mara Persano, MD, University Of Cagliari, Cagliari, Italy, discusses a real-world study comparing first-line lenvatinib vs. atezolizumab plus bevacizumab for patients with hepatocellular carcinoma (HCC). More than 2000 patients across Italy, Germany, Republic of Korea, and Japan were involved in the study; 1300 received lenvatinib and 800 received atezolizumab plus bevacizumab. The primary endpoint of the study was objective response rate (ORR), with overall survival (OS) being a secondary endpoint. The lenvatinib cohort achieved a higher ORR compared to those receiving atezolizumab plus bevacizumab. This interview took place at the European Society for Medical Oncology (ESMO) Asia congress 2022 in Singapore.
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