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GU Cancers 2026 | Predicting the future role microbiome-modulating treatments in kidney cancer

Miguel Zugman, MD, Albert Einstein Israelite Hospital, Sao Paolo, Brazil, comments on the potential of microbiome-modulating interventions in kidney cancer and the need to understand the underlying mechanisms behind their clinical benefits. While these strategies are universal and safe, further research is needed to identify patients who can benefit the most and potentially escalate other microbiome-modulating interventions. This interview took place at the 2026 ASCO GU Cancers Symposium in San Francisco, CA.

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Transcript

I think there’s a lot of work there to be done in understanding what are the mechanisms behind the clinical signal and encouraging results that we’ve been seeing with the use of microbiome-modulating interventions and also, as you said, in identifying the patients who can benefit the most. But since these strategies really are very universal and safe, I think the idea will be to further spread this use among all comers, but maybe identifying patients who can benefit from even escalating other possible interventions that also modulate the microbiome...

I think there’s a lot of work there to be done in understanding what are the mechanisms behind the clinical signal and encouraging results that we’ve been seeing with the use of microbiome-modulating interventions and also, as you said, in identifying the patients who can benefit the most. But since these strategies really are very universal and safe, I think the idea will be to further spread this use among all comers, but maybe identifying patients who can benefit from even escalating other possible interventions that also modulate the microbiome.

This transcript is AI-generated. While we strive for accuracy, please verify this copy with the video.

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