ASCO 2023 | Advancing ADC therapy

Valentina Boni, MD, PhD, University Hospital Quironsalud Madrid, Madrid, Spain, discusses the importance of discovering new targets for advancing antibody-drug conjugate (ADC) therapy. Dr Boni highlights the recent changes in the landscape of ADCs following the approval of trastuzumab deruxtecan (TDM-1) for breast cancer, including the development of ASC targeting novel targets such as Claudin-2, MET and B7-H3. These ADCs utilize innovative payloads and aim to address new indications including small cell lung cancer (SCLC), colorectal cancer, and gastric cancer. This interview took place at the American Society of Clinical Oncology (ASCO) 2023 Annual Congress in Chicago, IL.

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