ECC 2015 | CheckMate 025: Phase 3 trial of nivolumab for advanced kidney cancer

Padmanee Sharma

CheckMate 025, a phase 3 clinical trial, compared the anti-programmed cell death protein-1 (PD-1) antibody, nivolumab, with the standard treatment, everolimus, in patients with clear cell renal cell carcinoma. CheckMate 025 is the first clinical trial to show an improvement in overall survival in these patients for any immune checkpoint inhibitor agent. The survival benefit was seen in patients regardless of the extent of the PD-1 ligand expression in their tumors.

Presented at the European Cancer Conference (ECC) 2015 by Padmanee Sharma, MD, PhD, of The University of Texas MD Anderson Cancer Center, Houston, TX

Share this video  
Similar topics

Sign-up for our Newsletter!

Keep up to date with all the latest news with our monthly newsletter