Ruman Rahman, PhD, University of Nottingham, Nottingham, UK, discusses using spatially resolved transcriptomics to find the molecular features of infiltrative tumor cells associated with recurring glioblastoma. Fluorescence-guided neurosurgery with 5-aminolevulinic acid (5-ALA) enables the detection of infiltrative tumor cells, where the tumors cells that have not been resected will fluoresce as a result of differential expression of certain genes. This interview took place at the British Neuro-Oncology Society (BNOS) Annual Meeting 2022.