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ASCO 2024 | Infliximab versus vedolizumab for ICI colitis: a randomized clinical trial overview

Yinghong Wang, MD, PhD, The University of Texas MD Anderson Cancer Center, Houston, TX, discusses a randomized clinical trial (NCT04407247) comparing infliximab and vedolizumab for immune checkpoint inhibitor (ICI) colitis. The trial explores how these treatments, targeting different pathways, affect colitis symptoms, treatment efficacy, and patient outcomes. Current treatments often involve immunosuppressants, which can lead to immune-related adverse events (irAEs), complicating cancer therapy. This interview took place during the 2024 ASCO Meeting in Chicago, IL.

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Consulting or Advisory Role – BioNTech; Ilya Pharma; IOTA Pharmaceuticals; Janssen; Kanvas Biosciences; Mallinckrodt; Sorriso Pharmaceuticals
Patents, Royalties, Other Intellectual Property – Springer