Alexis LeVee, MD, City of Hope, Duarte, CA, comments on the incidence and predictors of immune-related adverse events (irAE) in patients with early-stage breast cancer treated with immune checkpoint inhibitors. Findings from a cohort of patients reveal that a majority experienced irAE, which is higher than the reported rate in the KEYNOTE-522 trial (NCT03036488). Older age and comorbidities such as chronic kidney disease were also risk factors for severe irAE. This interview took place at the 2024 San Antonio Breast Cancer Symposium (SABCS) congress in San Antonio, TX.
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