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GU Cancers 2025 | Examining the role of liquid biopsy in renal cell carcinoma

Chinmay Jani, MBBS, Sylvester Comprehensive Cancer Center, Doral, FL, describes a review on the evolving role of liquid biopsy in cancer diagnostics, prognostics, and treatment decision-making in renal cell carcinoma (RCC). Dr Jani highlights the potential of various liquid biopsy components, including circulating tumor DNA (ctDNA), cell-free DNA, and circulating tumor RNA (ctRNA), in detecting novel alterations and guiding personalized treatment approaches. By analyzing multiple studies, this review provides a narrative overview of current advancements and emerging platforms in liquid biopsy. This interview took place at the ASCO GU Cancers Symposium 2025 in San Francisco, CA.

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