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ESMO 2025 | EMBARK: metastasis-free survival by prior treatment in hrBCR prostate cancer

Neal Shore • 19 Oct 2025
ESMO 2025
Genitourinary Cancer Prostate Cancer Enzalutamide Mevrometostat
EMBARK

Neal Shore, MD, FACS, Carolina Urologic Research Center, Myrtle Beach, SC, discusses a post hoc analysis of the Phase III EMBARK trial (NCT02319837), evaluating metastasis-free survival by prior definitive therapy in patients with high-risk biochemically recurrent (hrBCR) prostate cancer. Across subgroups receiving radical prostatectomy, radiotherapy, or both, enzalutamide plus leuprolide consistently improved metastasis-free survival versus leuprolide alone. This interview took place at the European Society for Medical Oncology (ESMO) 2025 Congress in Berlin, Germany.

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