Kevin Zarrabi, MD, MS, FACP, Sidney Kimmel Cancer Center, Philadelphia, PA, discusses the progress of T-cell redirecting therapies in prostate cancer, noting the transition from early to late phase clinical development and potential regulatory approval. There has been a growth in the number of trials, driven by the discovery of novel tumor antigens in prostate cancer, and Phase I trials have demonstrated that T-cell engagers can overcome the conventional notion that prostate cancer is immune-cold or resistant to immunotherapies. This interview took place at the 8th International Workshop on CAR-T and Bispecifics 2026, in Tampa, FL
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