ASCO GI 2023 | Claudin 18.2 as an emerging target in gastrointestinal cancers

David Bing Zhen, MD, University of Washington Medicine, Seattle, WA, describes the rationale behind targeting claudin 18.2 in gastrointestinal cancers. Claudin 18.2 is a tight-junction protein that is highly expressed in cancers, and has subsequently become a promising target. Dr Zhen highlights multiple monoclonal antibodies and cellular immunotherapies in development that may especially benefit pre-treated patients. This interview took place at the American Society of Clinical Oncology (ASCO) 2023 Gastrointestinal Cancers (GI) Symposium in San Francisco, CA.

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