David Bing Zhen, MD, University of Washington Medicine, Seattle, WA, comments on the future of cellular therapies in gastrointestinal malignancies. Despite CAR-T cell therapies having more success in hematological malignancies, recent strategies have enabled cellular immunotherapies across different modalities to be viable in solid tumors, such as targeting anti-claudin 18.2 in gastric cancer and elucidating novel biomarkers of efficacy. This interview took place at the American Society of Clinical Oncology (ASCO) 2023 Gastrointestinal Cancers (GI) Symposium in San Francisco, CA.
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