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ESMO Asia | Novel immune checkpoint inhibitor combinations for TNBC treatment

Michail Ignatiadis, MD, PhD, Institut Jules Bordet, Brussels, Belgium, discusses novel combinations of immune checkpoint inhibitors in triple-negative breast cancer (TNBC) treatment. The KEYNOTE-522 (NCT03036488) regimen combines pembrolizumab with weekly paclitaxel and carboplatin, followed by anthracycline-based therapy. Studies are combining all effective immunotherapies and working to address to what extent they can replace doxorubicin and cyclophosphamide (AC), and if antibody-drug conjugates can be used rather than traditional chemotherapy. This interview took place at the European Society for Medical Oncology (ESMO) Asia 2023 Congress in Singapore.

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