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ASCO 2025 | Addressing alcohol use to reduce cancer risk

Chinmay Jani, MBBS, Sylvester Comprehensive Cancer Center, Doral, FL, comments on the importance of counseling patients about alcohol use, particularly those with a personal or family history of alcohol-related malignancies. Dr Jani emphasizes that alcohol is a significant risk factor for cancer and recommends that patients with a history of alcohol-related malignancies be more aware of their risk, while also advising them to cut down their drinking as much as possible until more data is available. By raising awareness and promoting prevention, Dr Jani believes that many cancer cases can be prevented, ultimately reducing cancer mortality. This interview took place during the 2025 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

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Transcript

Through our study, we are creating a highlight. We are highlighting that alcohol is a big risk factor. With that, again, we need to do more and more studies to identify who is the high-risk population. But the question that you ask about those patients who already have a history, one might assume that, yes, they are at high risk. Some who have particular genetic mutations from before as well, they might be at high risk as well...

Through our study, we are creating a highlight. We are highlighting that alcohol is a big risk factor. With that, again, we need to do more and more studies to identify who is the high-risk population. But the question that you ask about those patients who already have a history, one might assume that, yes, they are at high risk. Some who have particular genetic mutations from before as well, they might be at high risk as well. So those patient populations should be more and more aware about it. Still, we have further data on identifying how much level is like a safe level. What we are recommending is whatever you are drinking right now, you should for sure cut it down as much as possible. And till we have exact data, try to abstain as much as you can. More and more awareness needs to be created because again, this is not just about the prohibition of drinking alcohol, it’s more about the prevention of this cancer. We are able to prevent it so many cancer cases might not even arise and therefore won’t even lead to cancer mortality.

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