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WCLC 2025 | Elucidating the case of higher lung cancer risk in East/Southeast Asians
Mattias Johansson, PhD, International Agency for Research on Cancer, Lyon, France, comments on the higher lung cancer risk amongst never-smokers in East/Southeast Asians, suggesting that air pollution, indoor cooking with poor ventilation, and genetic differences may be contributing factors. Dr Johansson notes that their research models the risk specifically for Southeast Asian populations, aiming to capture the unique risks associated with air pollution and other environmental factors. This interview took place at 2025 World Conference on Lung Cancer (WCLC) in Barcelona, Spain.
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Transcript
This has been a question that has been sort of an enigma in lung cancer research. Why do Southeast Asian people have a higher risk? There could be many reasons. Air pollution has been hypothesized as being one of those reasons. Indoor cooking with poor ventilation has been a hypothesis. Perhaps there are genetic differences and so forth. If we take our data into account, as well as other studies, it seems that perhaps air pollution is a likely factor...
This has been a question that has been sort of an enigma in lung cancer research. Why do Southeast Asian people have a higher risk? There could be many reasons. Air pollution has been hypothesized as being one of those reasons. Indoor cooking with poor ventilation has been a hypothesis. Perhaps there are genetic differences and so forth. If we take our data into account, as well as other studies, it seems that perhaps air pollution is a likely factor. We’re not looking at that explicitly in our model. But what we’re doing to capture that risk is to model the risk specifically for Southeast Asian populations. So that’s one way where we can hopefully capture whatever risk comes from air pollution, for instance, into accurate risk prediction models. Thank you.
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