Here, Celia Diez de los Rios, ANP, from the University of Southampton NHS Foundation Trust, Southampton, UK, discusses the impact of novel cancer therapies on the role of nurses. Speaking at the European Lung Cancer Congress (ELCC) 2019, held in Geneva, Switzerland, Ms de los Rios explains how the introduction of new immunotherapies in particular has led to changes in treatment duration, side effects observed, and the challenges faced.