Rachael Louise Murray, PhD, FRCR, MRCP, MB ChB, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, talks on future directions and remaining questions following the results of the Yorkshire Enhanced Stop Smoking Study (YESS) (NCT03750110), including whether there needs to be gender-specific intervention. This interview took place at the IASLC 2022 World Conference on Lung Cancer congress in Vienna, Austria.