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AACR 2025 | CLONEVO: pre-operative abemaciclib in cisplatin-ineligible MIBC

Bishoy Faltas • 10 Apr 2025
AACR 2025
Bladder Cancer Genitourinary Cancer Abemaciclib
CLONEVO

Bishoy Faltas, MD, Weill Cornell Medicine, New York, NY, the CLONEVO trial (NCT03837821), evaluating short-term pre-operative abemaciclib in cisplatin-ineligible patients with muscle-invasive bladder cancer (MIBC). Treatment led to encouraging rates of pathologic response and ctDNA clearance, with modulation of key proliferation and DNA repair pathways. This interview took place at American Association for Cancer Research (AACR) Annual Meeting 2025 in Chicago, IL.

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