ESMO WCGIC 2023 | Advances in FGFR inhibition for hepatobiliary cancer

Arndt Vogel, MD, Hannover Medical School, Hannover, Germany, discusses the latest developments in FGFR inhibition for patients with hepatobiliary cancer. The phase 2 FIGHT-202 trial (NCT02924376) of pemigatinib demonstrated survival benefit in patients with previously treated advanced cholangiocarcinoma, and futibatinib has been approved by the FDA for FGFR2-mutant cholangiocarcinoma. RLY-4008 is another highly selective, potent FGFR2 inhibitor, which can reduce off-target toxicity. This interview took place at the ESMO World Congress on Gastrointestinal Cancer (WCGIC) 2023 in Barcelona, Spain.

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