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ASCO 2024 | The future of OBX-115, a novel TIL, in the melanoma treatment landscape

Rodabe Navroze Amaria, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, comments on how OBX-115, an IL2-sparing autologous engineered tumor-infiltrating lymphocyte (TIL), can provide a potential treatment alternative for patients with melanoma. Whilst findings from the Phase I study (NCT05470283) show encouraging outcomes, more research is needed. An ongoing Phase I/II multicenter study (NCT06060613) is underway. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

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Disclosures

Consulting or Advisory Role – Bristol-Myers Squibb/Medarex; Erasca, Inc; Iovance Biotherapeutics; Novartis; Obsidian Therapeutics
Research Funding – Bristol-Myers Squibb (Inst); Genentech (Inst); iovance Biotherapeutics (Inst); KSQ Therapeutics (Inst); Novartis (Inst); Obsidian Therapeutics (Inst); OnKure (Inst)