GU Cancers 2019 | “All bladder, all the time” – Highlights from the 2019 Genitourinary Cancers Symposium

Arlene Siefker-Radtke

Arlene Siefker-Radtke, MD of the University of Texas MD Anderson Cancer Center, Houston, TX, speaks at the 2019 Genitourinary Cancers Symposium, held in San Francisco, CA. She gives us a rundown of her top picks from the conference and comments on the future directions for the treatment of bladder cancer.

Transcript (edited for clarity):

At this meeting, we are certainly seeing the development of multiple novel targeted strategies. There was data presented on Sacituzumab, which is an antibody-drug conjugate. And the goal of antibody-drug conjugates are to bring a payload of a toxic agent directly to the tumor, thereby minimizing the toxicity that patients experience.

With Sacituzumab, we’re seeing response rates in the range of 27% and a toxicity profile that when compared to historical data with MVAC and Gemcitabine Cisplatin certainly appears promising. So I’m looking forward to hearing more about Sacituzumab in the future.

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